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Clofranil®

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10mg
50mg

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30 Tabletten
360 Tabletten
10mg Tabletten
30 Tabletten
AirMail
€13
EMS
€22
EUR 1.18

pro Tablette

EUR 44.18 -20%
EUR 35.34pro Packung
Jetzt bestellen
60 Tabletten
AirMail
€13
EMS
€22
EUR 0.89

pro Tablette

EUR 66.76 -20%
EUR 53.40pro Packung

Sie sparen EUR 17.28

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BESTEN KAUF
90 Tabletten
AirMail
€13
EMS
€22
EUR 0.79

pro Tablette

EUR 88.35 -20%
EUR 70.68pro Packung

Sie sparen EUR 35.34

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120 Tabletten
AirMail
€13
EMS
€22
EUR 0.71

pro Tablette

EUR 106.02 -20%
EUR 84.82pro Packung

Sie sparen EUR 56.55

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180 Tabletten
AirMail
€13
EMS
€22
EUR 0.67

pro Tablette

EUR 150.20 -20%
EUR 120.16pro Packung

Sie sparen EUR 91.89

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240 Tabletten
AirMail
€13
EMS
€22
EUR 0.63

pro Tablette

EUR 188.49 -20%
EUR 150.79pro Packung

Sie sparen EUR 131.94

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270 Tabletten
AirMail
€13
EMS
€22
EUR 0.59

pro Tablette

EUR 198.79 -20%
EUR 159.03pro Packung

Sie sparen EUR 159.04

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360 Tabletten
AirMail
€13
EMS
€22
EUR 0.55

pro Tablette

EUR 247.39 -20%
EUR 197.91pro Packung

Sie sparen EUR 226.18

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25mg Tabletten
30 Tabletten
AirMail
€13
EMS
€22
EUR 1.47

pro Tablette

EUR 54.98 -20%
EUR 43.98pro Packung
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60 Tabletten
AirMail
€13
EMS
€22
EUR 1.30

pro Tablette

EUR 97.19 -20%
EUR 77.75pro Packung

Sie sparen EUR 10.21

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BESTEN KAUF
90 Tabletten
AirMail
€13
EMS
€22
EUR 1.22

pro Tablette

EUR 137.44 -20%
EUR 109.95pro Packung

Sie sparen EUR 21.99

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120 Tabletten
AirMail
€13
EMS
€22
EUR 1.18

pro Tablette

EUR 176.71 -20%
EUR 141.36pro Packung

Sie sparen EUR 34.56

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180 Tabletten
AirMail
€13
EMS
€22
EUR 1.13

pro Tablette

EUR 253.28 -20%
EUR 202.62pro Packung

Sie sparen EUR 61.26

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240 Tabletten
AirMail
€13
EMS
€22
EUR 1.08

pro Tablette

EUR 323.96 -20%
EUR 259.17pro Packung

Sie sparen EUR 92.67

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270 Tabletten
AirMail
gratis
EMS
€13
EUR 1.04

pro Tablette

EUR 350.47 -20%
EUR 280.37pro Packung

Sie sparen EUR 115.45

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360 Tabletten
AirMail
gratis
EMS
gratis
EUR 0.99

pro Tablette

EUR 447.66 -20%
EUR 358.12pro Packung

Sie sparen EUR 169.64

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50mg Tabletten
30 Tabletten
AirMail
€13
EMS
€22
EUR 2.02

pro Tablette

EUR 75.59 -20%
EUR 60.47pro Packung
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60 Tabletten
AirMail
€13
EMS
€22
EUR 1.88

pro Tablette

EUR 141.36 -20%
EUR 113.09pro Packung

Sie sparen EUR 7.85

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BESTEN KAUF
90 Tabletten
AirMail
€13
EMS
€22
EUR 1.81

pro Tablette

EUR 203.21 -20%
EUR 162.57pro Packung

Sie sparen EUR 18.85

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120 Tabletten
AirMail
€13
EMS
€22
EUR 1.77

pro Tablette

EUR 265.06 -20%
EUR 212.05pro Packung

Sie sparen EUR 29.84

Jetzt bestellen
180 Tabletten
AirMail
gratis
EMS
€13
EUR 1.73

pro Tablette

EUR 388.75 -20%
EUR 311.00pro Packung

Sie sparen EUR 51.83

Jetzt bestellen
240 Tabletten
AirMail
gratis
EMS
gratis
EUR 1.69

pro Tablette

EUR 506.56 -20%
EUR 405.25pro Packung

Sie sparen EUR 78.54

Jetzt bestellen
270 Tabletten
AirMail
gratis
EMS
gratis
EUR 1.65

pro Tablette

EUR 556.62 -20%
EUR 445.30pro Packung

Sie sparen EUR 98.96

Jetzt bestellen
360 Tabletten
AirMail
gratis
EMS
gratis
EUR 1.57

pro Tablette

EUR 706.82 -20%
EUR 565.46pro Packung

Sie sparen EUR 160.21

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Description

Clofranil® is manufactured by Sun Pharmaceuticals. Its active constituent is Clomipramine, a tricyclic antidepressant (TCA).

Indications:

- depression or MDD (major depressive disorder) – feeling sad, inability to sleep properly or to enjoy life as one used to);

- OCD (obsessive compulsive disorders), or obsessive states (compulsive or irrational preoccupation);

- phobias (strong fear of something, which is actually irrational);

- cataplexy associated with narcolepsy. Cataplexy is a condition characterized by abrupt loss of muscle tone, associated with narcolepsy (sudden and uncontrolled attacks of deep sleep), often caused by strong emotion like laughter;

- off-label treatment of premature ejaculation (PE), (or too early ejaculation within 1 minute after penetration). Clomipramine is able to prolong the coitus time.

MOA (mechanism of action):

Clomipramine enhances the actions of norepinephrine and serotonin (chemical neurotransmitters in the brain used by nerves to communicate with each other) by blocking their reuptake and prolonging their activity. Clomipramine also has a wide pharmacological spectrum of action, which includes alpha1- adrenolytic, anticholinergic, antihistaminic, and antiserotonergic (5-HT-receptor blocking) properties.

Dosage

Clofranil® is used only in adults over 17 years of age.

Swallow Clofranil® tablet whole with a drink of water.

For depression: initially 10 mg, which can be increased to find a dose that works for you. This is normally 30-150 mg daily, maximum of 250 mg daily for severe conditions.

For obsessions and phobias: initially 25 mg, which can be increased to 100-150 mg daily.

For cataplexy: initially 10 mg, which can be increased to a maximum of 75 mg daily.

Elderly patients often need a lower dose. The maximum dose for elderly patients is 75 mg daily.

Precautions:

It can take 4 to 6 weeks for Clofranil® to start working. You should continue the treatment for at least 6 months after you feel better to stop depression from coming back.

Clofranil® can make feel sleepy so a doctor may advise patient taking a small dose when starting treatment. Then the dose can be increased gradually as the body gets used to it.

When stopping treatment with Clofranil®, it is best to decrease the dose gradually over a period of several weeks or months to minimize the withdrawal reactions.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Clofranil® to compensate the missed dose.

Overdose

If you take an overdose of Clofranil®, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Clofranil® are:

  • allergic reactions
  • dry mouth
  • constipation
  • blurred vision
  • feeling sleepy
  • dizzy or tired
  • headache
  • feeling faint or light-headed
  • nausea
  • vomiting
  • diarrhea
  • sweating
  • hot flushes
  • difficulty in passing urine
  • increased appetite
  • feeling confused
  • feeling anxious or restless
  • disturbed sleep
  • lack of concentration
  • feeling shaky
  • muscle weakness
  • itchy skin rash
  • weight changes
  • changes in sexual function
  • breast tenderness
  • changes in taste
  • ringing in ears
  • yawning

Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Clofranil® if you are allergic to Clomipramine or any of the other ingredients in the tablets.

Do not take Clofranil® if you are taking or have taken other antidepressants like monoamine oxidase inhibitor drug (MAOI) (selegiline, moclobemide), or MAOI-like drug (linezolid) for depression, SSRI antidepressants (dapoxetine, fluoxetine, duloxetine).

Do not take Clofranil® if you have an overactive thyroid gland.

Do not take Clofranil® if you have liver disorders, epilepsy, diabetes mellitus, glaucoma, constipation over a long time, heart disorder or blood vessel disease.

Do not take Clofranil® if you have any difficulties passing urine, or if you have had prostate trouble.

Do not take Clofranil® if you have or have had a mental health problem (in particular, bipolar disorder or psychosis, schizophrenia).

If you have been told you have phaeochromocytoma, a tumor on your adrenal gland.

Do not take Clofranil® if you have porphyria, a rare inherited blood disorder.

Do not take Clofranil® if you have ever had suicidal thoughts.

Do not take Clofranil® if you have had a head injury or have suffered brain damage.

Do not take Clofranil® if you are going to have electric shock therapy (ECT).

Do not take Clofranil® if you have been told you have a low level of potassium in your blood (hypokalemia).

Clofranil® is only for use in adults over 17 years of age.

Do not take Clofranil® if you are pregnant, likely to become pregnant or are breastfeeding until your doctor decides if this medication is right for you.

Do not drive or operate machinery while treatment with Clofranil®.

Consult your doctor prior taking Clofranil® if you are taking any of the following medications: drugs for other mental health conditions (thioridazine, lithium, clozapine, pimozide, benzodiazepines), drugs for high blood pressure (guanethidine, betanidine, reserpine, clonidine or alpha methyldopa or norepinephrine), norepinephrine (noradrenaline) for low blood pressure, drugs for abnormal heart rhythm (disopyramide, procainamide, epinephrine (adrenaline), isoprenaline, amiodarone, quinidine, diltiazem and verapamil), beta-blockers (atenolol, sotalol), anticoagulants (warfarin), non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin, drugs for Parkinson's Disease (levodopa, biperiden, entacapone or selegiline), nicotine for nicotine replacement therapy, anticonvulsants (barbiturates), decongestants for colds and flu (ephedrine, phenylephrine), cimetidine for stomach ulcers or heartburn, methylphenidate used to treat ADHD, rifampicin for tuberculosis (TB), quinine, strong painkillers (tramadol, nefopam, morphine, codeine), narcotics (ecstasy), atropine or similar medicines (including eye drops), contraceptive pills or hormone replacement therapy, drugs for HIV (ritonavir, indinavir), terbinafine for fungal infections, colestipol and cholestyramine for high cholesterol levels, St. John’s wort (Hypericum perforatum), disulfiram for alcoholism, altretamine, baclofen, pentamidine for pneumonia, levacetylmethadol used to treat addiction to opioid drugs such as heroin.

Q: What is Clofranil®?

A: Clofranil® is an effective psychiatric drug used to treat depression, obsessive compulsive states, phobias, cataplexy associated with narcolepsy. Clofranil® is suitable only for adults for long-term treatment, that is determined by the doctor.

Q: Does Clofranil® cause dependence?

A: Clofranil® is not addictive. However, sudden stopping or decrease in dose of Clofranil® may cause withdrawal reactions like dizziness, numbness, sleep disturbances, agitation or anxiety, headaches, nausea, vomiting and shaking. Consult the doctor regarding the use of Clofranil® and discontinuation.

Q: Is Clofranil® a narcotic?

A: Clofranil® is a tricyclic antidepressant. It treats depression through inhibiting the neuronal re-uptake of chemical substances present in the brain called noradrenaline and mainly serotonin (SSRI). It is not a narcotic.

Zielort Versandart Verfolgung Lieferzeit Preis
Weltweit Lieferung

Weltweit Lieferung

Einschreiben  Nicht verfolgbar 14-21 Werktage EUR 13.20 pro bestellung
EMS  Verfolgbar, sofern vorhanden 5-9 Werktage EUR 22.00 pro bestellung

Lieferzeit beträgt:

Einschreiben - 14-21 Werktage, preis - EUR 13.20, Keine Unterschrift ist beim Empfang erforderlich.
EMS - 5-9 Werktage, preis - EUR 22.00, Unterschrift ist beim Empfang erforderlich.
Ihre Bestellung wird sicher verpackt und binnen 24 Stunden versendet.

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